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Industry Trends

Why AI Is Reinventing How Businesses Buy Everything

a16z · Oct 02, 2026 · Industry Trends

AI agents are taking over end-to-end corporate procurement, starting with human-in-the-loop trust-building

“We're going to take control of this entire process from start to finish.”

A16z partner Sima Embl and Leo CEO Vlad Kyle discuss how AI agents are transforming corporate procurement by automating multi-stakeholder workflows across legal, finance, and supplier systems. The conversation highlights a trust-building playbook where AI starts human-in-the-loop and earns autonomy through thousands of negotiations. The broader strategic question—whether AI startups can survive when incumbents like Salesforce add AI on top—frames the vertical AI moat debate.

procurement vertical-ai agentic-ai enterprise human-in-the-loop a16z

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